| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FASTKD1 |
| Gene ID: | 79675 |
| Uniprot ID: | FAKD1_HUMAN |
| Immunogen Region: | 638-847 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 638-847 of human FASTKD1 (NP_078898.3). |
| Immunogen Sequence: | KFLARLDSQLEILSPSRSAR VQFHLMELNRSVCLECPEFQ IPWFHDRFCQQYNKGIGGMD GTQQQIFKMLAEVLGGINCV KASVLTPYYHKVDFECILDK RKKPLPYGSHNIALGQLPEM PWESNIEIVGSRLPPGAERI ALEFLDSKALCRNIPHMKGK SAMKKRHLEILGYRVIQISQ FEWNSMALSTKDARMDYLRE CIFGEVKSCL |
| Tissue Specificity | Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart. |
| Function | Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity. |
| Protein Name | Fast Kinase Domain-Containing Protein 1 - Mitochondrial |
| Cellular Localisation | MitochondrionPreferentially Localizes To Mitochondrial Rna GranulesPlatforms For Post-Transcriptional Rna Modification And Ribosome Assembly |
| Alternative Antibody Names | Anti-Fast Kinase Domain-Containing Protein 1 - Mitochondrial antibodyAnti-FASTKD1 antibodyAnti-KIAA1800 antibody |
Information sourced from Uniprot.org
