Anti-Fascin antibody [IHC573] (STJA0042167)

SKU:
STJA0042167
£111.50 - £269.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: IHC-p
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-Fascin for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : IHC573
Conjugation: Unconjugated
Formulation: Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Storage Instruction: Store at 2-8°C for up to 1 year. Do not freeze.
Gene Symbol: FSCN1
Gene ID: 6624
Uniprot ID: FSCN1_HUMAN
Specificity: Tested and validated on hodgkin's lymphoma, tonsil tissue.
Tissue Specificity Ubiquitous.
Post Translational Modifications Phosphorylation at Ser-39 inhibits actin-binding. Phosphorylation is required for the reorganization of the actin cytoskeleton in response to NGF.
Function Actin-binding protein that contains 2 major actin binding sites. Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF.
Protein Name Fascin
55 Kda Actin-Bundling Protein
Singed-Like Protein
P55
Database Links Reactome: R-HSA-6785807
Cellular Localisation Cytoplasm
Cytosol
Cell Cortex
Cytoskeleton
Stress Fiber
Cell Projection
Filopodium
Invadopodium
Microvillus
Cell Junction
Colocalized With Rufy3 And F-Actin At Filipodia Of The Axonal Growth Cone
Colocalized With Dbn1 And F-Actin At The Transitional Domain Of The Axonal Growth Cone
Alternative Antibody Names Anti-Fascin antibody
Anti-55 Kda Actin-Bundling Protein antibody
Anti-Singed-Like Protein antibody
Anti-P55 antibody
Anti-FSCN1 antibody
Anti-FAN1 antibody
Anti-HSN antibody
Anti-SNL antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ16101740 Anti-Fascin antibody [IM20] (STJ16101740) Mouse Monoclonal Human IHC-P/WB
STJA0005027 Anti-Fascin antibody [SM5027] (STJA0005027) Mouse Monoclonal Human IHC/IF
STJA0039141 Anti-Fascin antibody [PT0620R] (STJA0039141) Rabbit Monoclonal Human/Mouse/Rat WB/IHC/IF/IP/ELISA
STJA0010413 Anti-Fascin antibody [SM0413] (STJA0010413) Mouse Monoclonal Human WB/IHC/IF
STJA0005195 Anti-Fascin antibody [SM5195] (STJA0005195) Mouse Monoclonal Human/Mouse/Rat WB

Related Products

!