| Short Description : | Rabbit polyclonal FANCG (343-622) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FANCG |
| Gene ID: | 2189 |
| Uniprot ID: | FANCG_HUMAN |
| Immunogen Region: | 343-622 |
| Immunogen Sequence: | QSQTKHILASRCLQTGRAGD AAEHYLDLLALLLDSSEPRF SPPPSPPGPCMPEVFLEAAV ALIQAGRAQDALTLCEELLS RTSSLLPKMSRLWEDARKGT KELPYCPLWVSATHLLQGQA WVQLGAQKVAISEFSRCLEL LFRATPEEKEQGAAFNCEQG CKSDAALQQLRAAALISRGL EWVASGQDTKALQDFLLSVQ MCPGNRDTYFHLLQTLKRLD RRDEATALWWRLEAQTKGS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 343-622 of human FANCG (NP_004620.1). |
| Tissue Specificity | Highly expressed in testis and thymus. Found in lymphoblasts. |
| Function | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene. |
| Protein Name | Fanconi Anemia Group G ProteinProtein FacgDna Repair Protein Xrcc9 |
| Database Links | Reactome: R-HSA-6783310Reactome: R-HSA-9833482 |
| Cellular Localisation | NucleusCytoplasmThe Major Form Is NuclearThe Minor Form Is Cytoplasmic |
| Alternative Antibody Names | Anti-Fanconi Anemia Group G Protein antibodyAnti-Protein Facg antibodyAnti-Dna Repair Protein Xrcc9 antibodyAnti-FANCG antibodyAnti-XRCC9 antibody |
Information sourced from Uniprot.org
