| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Acylpyruvase FAHD1, mitochondrial is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FAHD1 |
| Gene ID: |
81889 |
| Uniprot ID: |
FAHD1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of FAHD1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human FAHD1 |
| Function | Tautomerase that converts enol-oxaloacetate, a strong inhibitor of succinate dehydrogenase, to the physiological keto form of oxaloacetate. It is thereby required to maximize aerobic respiration efficiency by preventing succinate dehydrogenase inhibition. Also acts as a weak oxaloacetate decarboxylase (ODx), catalyzing the decarboxylation of oxaloacetate (OAA) to pyruvate and CO(2), and as such is likely a regulatory enzyme in the TCA cycle. Also displays acylpyruvase activity, being able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Exhibits only a weak hydrolase activity on methylacetopyruvate and acetylacetone, and no activity toward acetoacetyl-CoA. |
| Protein Name | Oxaloacetate Tautomerase Fahd1 - MitochondrialAcylpyruvase Fahd1Fumarylacetoacetate Hydrolase Domain-Containing Protein 1Fah Domain-Containing Protein 1Oxaloacetate DecarboxylaseOaa DecarboxylaseOdxYisk-Like Protein |
| Database Links | Reactome: R-HSA-70268 |
| Cellular Localisation | MitochondrionCytoplasmCytosol |
| Alternative Antibody Names | Anti-Oxaloacetate Tautomerase Fahd1 - Mitochondrial antibodyAnti-Acylpyruvase Fahd1 antibodyAnti-Fumarylacetoacetate Hydrolase Domain-Containing Protein 1 antibodyAnti-Fah Domain-Containing Protein 1 antibodyAnti-Oxaloacetate Decarboxylase antibodyAnti-Oaa Decarboxylase antibodyAnti-Odx antibodyAnti-Yisk-Like Protein antibodyAnti-FAHD1 antibodyAnti-C16orf36 antibodyAnti-YISKL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
