Anti-F13A1 antibody (1-50) {Biotin} (STJ501107)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenMulti-epitope synthetic peptides were used: amino acid range 1-50 and 700-732. A mixture of synthetic peptides used for FXIIIA-101AP and FXIIIA-112AP.
General Information
| Short Description | Rabbit polyclonal antibody anti-F13A1 (1-50) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunohistochemistry, Immunofluorescence, Immunoprecipitation and Western Blot research applications. |
| Applications | CM/ELISA/ICC/IHC/IF/IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.55-0.75 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150IHC: 1:200ICC: 1:200IF: 1:200CFM: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | F13A1 |
| Gene ID | 2162 |
| Uniprot ID | F13A_HUMAN |
| Immunogen | Multi-epitope synthetic peptides were used: amino acid range 1-50 and 700-732. A mixture of synthetic peptides used for FXIIIA-101AP and FXIIIA-112AP. |
| Immunogen Region | 1-50 |
Additional Info
| Post Translational Modifications | The activation peptide is released by thrombin. |
| Function | Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. |
| Protein Name | Coagulation Factor Xiii A ChainCoagulation Factor XiiiaProtein-Glutamine Gamma-Glutamyltransferase A ChainTransglutaminase A Chain |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-140875Reactome: R-HSA-6785807 |
| Cellular Localisation | CytoplasmSecretedSecreted Into The Blood PlasmaCytoplasmic In Most TissuesBut Also Secreted In The Blood Plasma |
| Alternative Antibody Names | Anti-Coagulation Factor Xiii A Chain antibodyAnti-Coagulation Factor Xiiia antibodyAnti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibodyAnti-Transglutaminase A Chain antibodyAnti-F13A1 antibodyAnti-F13A antibody |
Information sourced from Uniprot.org