Anti-EXOC7 antibody (STJA0007348)

SKU:
STJA0007348
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Exocyst complex component 7 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EXOC7
Gene ID: 23265
Uniprot ID: EXOC7_HUMAN
Specificity: This antibody detects endogenous levels of Exo70 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human Exo70
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. It is required for neuron survival and plays an essential role in cortical development.
Protein Name Exocyst Complex Component 7
Exocyst Complex Component Exo70
Database Links Reactome: R-HSA-1445148
Reactome: R-HSA-264876
Reactome: R-HSA-5620916
Cellular Localisation Cytoplasm
Cytosol
Cell Membrane
Peripheral Membrane Protein
Midbody
Midbody Ring
Translocates
As A Preformed Complex With Exoc3/Sec6 And Exoc4/Sec8
To The Plasma Membrane In Response To Insulin Through The Activation Of Arhq
Colocalizes With Cntrl/Centriolin At The Midbody Ring
Alternative Antibody Names Anti-Exocyst Complex Component 7 antibody
Anti-Exocyst Complex Component Exo70 antibody
Anti-EXOC7 antibody
Anti-EXO70 antibody
Anti-KIAA1067 antibody

Information sourced from Uniprot.org

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