• Western blot analysis of extracts of various cell lines, using EXOC3 antibody (STJ11104117) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-EXOC3 antibody (650-745) [S4117RM] (STJ11104117)

SKU:
STJ11104117

£146.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Exocyst Complex Component 3 (650-745) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S4117RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EXOC3
Gene ID: 11336
Uniprot ID: EXOC3_HUMAN
Immunogen Region: 650-745
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 650-745 of human EXOC3 (O60645).
Immunogen Sequence: EDVDGYCDTIVAVAEVIKLT DPSLLYLEVSTLVSKYPDIR DDHIGALLAVRGDASRDMKQ TIMETLEQGPAQASPSYVPL FKDIVVPSLNVAKLLK
Tissue Specificity Expressed in epididymis (at protein level).
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Protein Name Exocyst Complex Component 3
Exocyst Complex Component Sec6
Database Links Reactome: R-HSA-1445148
Reactome: R-HSA-264876
Reactome: R-HSA-5620916
Cellular Localisation Cytoplasm
Perinuclear Region
Cell Projection
Growth Cone
Midbody
Golgi Apparatus
Neuron Projection
Perinuclear In Undifferentiated Cells
Redistributes To Growing Neurites And Growth Cones During Neuronal Differentiation
During Mitosis
Early Recruitment To The Midbody Requires Rala
But Not Ralb
And Exoc2
In Late Stages Of Cytokinesis
Localization To The Midbody Is Ralb-Dependent
Alternative Antibody Names Anti-Exocyst Complex Component 3 antibody
Anti-Exocyst Complex Component Sec6 antibody
Anti-EXOC3 antibody
Anti-SEC6 antibody
Anti-SEC6L1 antibody

Information sourced from Uniprot.org

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