| Host: |
Goat |
| Applications: |
Pep-ELISA/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-EVC2/Limbin (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
IHC-Recommended concentration, 2-4µg/mlELISA-antibody detection limit dilution 1:16000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
EVC2 |
| Gene ID: |
132884 |
| Uniprot ID: |
LBN_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_667338.3; NP_001159608.1 |
| Specificity: |
This antibody is expected to recognise isoform 1 (NP_667338.3) and isoform 2 (NP_001159608.1). |
| Immunogen Sequence: |
LNAKKAMRALGMD |
| Function | Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Plays a critical role in bone formation and skeletal development. May be involved in early embryonic morphogenesis. |
| Protein Name | LimbinEllis-Van Creveld Syndrome Protein 2Evc2 |
| Database Links | Reactome: R-HSA-5632684Reactome: R-HSA-5635838 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmCytoskeletonCilium Basal BodyCell ProjectionCiliumCilium MembraneNucleusThe Evc Complex Localizes At The Base Of Cilia In The Evc Zone Of Primary Cilia In A Efcab7-Dependent Manner |
| Alternative Antibody Names | Anti-Limbin antibodyAnti-Ellis-Van Creveld Syndrome Protein 2 antibodyAnti-Evc2 antibodyAnti-EVC2 antibodyAnti-LBN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
