| Tissue Specificity | Found in the heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Function | Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Plays a critical role in bone formation and skeletal development. May be involved in early embryonic morphogenesis. |
| Protein Name | LimbinEllis-Van Creveld Syndrome Protein 2Evc2 |
| Database Links | Reactome: R-HSA-5632684Reactome: R-HSA-5635838 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmCytoskeletonCilium Basal BodyCell ProjectionCiliumCilium MembraneNucleusThe Evc Complex Localizes At The Base Of Cilia In The Evc Zone Of Primary Cilia In A Efcab7-Dependent Manner |
| Alternative Antibody Names | Anti-Limbin antibodyAnti-Ellis-Van Creveld Syndrome Protein 2 antibodyAnti-Evc2 antibodyAnti-EVC2 antibodyAnti-LBN antibody |
Information sourced from Uniprot.org
