| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EVA1A |
| Gene ID: | 84141 |
| Uniprot ID: | EVA1A_HUMAN |
| Immunogen Region: | 90-152 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-152 of human EVA1A (NP_115557.1). |
| Immunogen Sequence: | DTVSDLSVRRHRRFERTLNK NVFTSAEELERAQRLEERER IIREIWMNGQPEVPGTRSLN RYY |
| Tissue Specificity | Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle. |
| Function | Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. |
| Protein Name | Protein Eva-1 Homolog AProtein Fam176aTransmembrane Protein 166 |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinLysosome Membrane |
| Alternative Antibody Names | Anti-Protein Eva-1 Homolog A antibodyAnti-Protein Fam176a antibodyAnti-Transmembrane Protein 166 antibodyAnti-EVA1A antibodyAnti-FAM176A antibodyAnti-TMEM166 antibodyAnti-SP24 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and CNPasease knockout (KO) HeLa cells, using [KO Validated] CNPase Rabbit polyclonal antibody (STJ119982) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/98767/382818/STJ119982_1__79726.1713151315.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CNPasease knockout (KO) HeLa cells, using [KO Validated] CNPase Rabbit polyclonal antibody (STJ119982) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.")
