Anti-ETS2 antibody (76-469) (STJ29468)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ETS2 (76-469) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ETS2 |
| Gene ID | 2114 |
| Uniprot ID | ETS2_HUMAN |
| Immunogen Region | 76-469 |
| Immunogen Sequence | KAVMSQALKATFSGFKKEQR RLGIPKNPWLWSEQQVCQWL LWATNEFSLVNVNLQRFGMN GQMLCNLGKERFLELAPDFV GDILWEHLEQMIKEN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 76-170 of human ETS2 (NP_005230.1). |
Additional Info
| Post Translational Modifications | Phosphorylation by CDK10 at Ser-220 and Ser-225 creates a phosphodegron that targets ETS2 for proteasomal degradation. |
| Function | Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription. |
| Protein Name | Protein C-Ets-2 |
| Database Links | Reactome: R-HSA-2559585 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein C-Ets-2 antibodyAnti-ETS2 antibody |
Information sourced from Uniprot.org