| Tissue Specificity | Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas. |
| Post Translational Modifications | Methylated. Trimethylation at Lys-200 and Lys-203 may negatively regulate the activity in electron transfer from acyl-CoA dehydrogenases. |
| Function | Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role. |
| Protein Name | Electron Transfer Flavoprotein Subunit BetaBeta-Etf |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-8876725 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Electron Transfer Flavoprotein Subunit Beta antibodyAnti-Beta-Etf antibodyAnti-ETFB antibodyAnti-FP585 antibody |
Information sourced from Uniprot.org
