Host: | Rabbit |
Applications: | WB/IHC-P/IP/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ETFA |
Gene ID: | 2108 |
Uniprot ID: | ETFA_HUMAN |
Immunogen Region: | 1-333 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-333 of human ETFA (NP_000117.1). |
Immunogen Sequence: | MFRAAAPGQLRRAASLLRFQ STLVIAEHANDSLAPITLNT ITAATRLGGEVSCLVAGTKC DKVAQDLCKVAGIAKVLVAQ HDVYKGLLPEELTPLILATQ KQFNYTHICAGASAFGKNLL PRVAAKLEVAPISDIIAIKS PDTFVRTIYAGNALCTVKCD EKVKVFSVRGTSFDAAATSG GSASSEKASSTSPVEISEWL DQKLTKSDRPELTGAKVVVS GGRGLKSGENFKLLYDLAD |
Post Translational Modifications | The N-terminus is blocked. |
Function | Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. |
Protein Name | Electron Transfer Flavoprotein Subunit Alpha - MitochondrialAlpha-Etf |
Database Links | Reactome: R-HSA-611105 |
Cellular Localisation | Mitochondrion Matrix |
Alternative Antibody Names | Anti-Electron Transfer Flavoprotein Subunit Alpha - Mitochondrial antibodyAnti-Alpha-Etf antibodyAnti-ETFA antibody |
Information sourced from Uniprot.org