| Host: |
Goat |
| Applications: |
Pep-ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-ERN2/IRE1b (Internal) is suitable for use in ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
ELISA-antibody detection limit dilution 1:4000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
ERN2 |
| Gene ID: |
10595 |
| Uniprot ID: |
ERN2_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_150296.3 |
| Immunogen Sequence: |
QKRLQSPSKQAQPLD |
| Function | Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins. |
| Protein Name | Serine/Threonine-Protein Kinase/Endoribonuclease Ire2Endoplasmic Reticulum-To-Nucleus Signaling 2Inositol-Requiring Protein 2Hire2pIre1-BetaIre1b Includes - Serine/Threonine-Protein Kinase - Endoribonuclease |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase/Endoribonuclease Ire2 antibodyAnti-Endoplasmic Reticulum-To-Nucleus Signaling 2 antibodyAnti-Inositol-Requiring Protein 2 antibodyAnti-Hire2p antibodyAnti-Ire1-Beta antibodyAnti-Ire1b Includes - Serine/Threonine-Protein Kinase - Endoribonuclease antibodyAnti-ERN2 antibodyAnti-IRE2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
