• Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ERN2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of A549 cells, using ERN2 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-ERN2 antibody (841-890 aa) (STJ93759)

SKU:
STJ93759

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Serine/threonine-protein kinase/endoribonuclease IRE2 (841-890 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ERN2
Gene ID: 10595
Uniprot ID: ERN2_HUMAN
Immunogen Region: 841-890 aa
Specificity: IRE1 Alpha/Beta Polyclonal Antibody detects endogenous levels of IRE1 Alpha/Beta protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ERN2 at the amino acid range 841-890
Function Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.
Protein Name Serine/Threonine-Protein Kinase/Endoribonuclease Ire2
Endoplasmic Reticulum-To-Nucleus Signaling 2
Inositol-Requiring Protein 2
Hire2p
Ire1-Beta
Ire1b Includes - Serine/Threonine-Protein Kinase - Endoribonuclease
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Serine/Threonine-Protein Kinase/Endoribonuclease Ire2 antibody
Anti-Endoplasmic Reticulum-To-Nucleus Signaling 2 antibody
Anti-Inositol-Requiring Protein 2 antibody
Anti-Hire2p antibody
Anti-Ire1-Beta antibody
Anti-Ire1b Includes - Serine/Threonine-Protein Kinase - Endoribonuclease antibody
Anti-ERN2 antibody
Anti-IRE2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance