| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-DNA repair endonuclease XPF (801-850 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ERCC4 |
| Gene ID: | 2072 |
| Uniprot ID: | XPF_HUMAN |
| Immunogen Region: | 801-850 aa |
| Specificity: | ERCC4 Polyclonal Antibody detects endogenous levels of ERCC4 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human XPF at the amino acid range 801-850 |
| Function | Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair, and which is essential for nucleotide excision repair (NER) and interstrand cross-link (ICL) repair. |
| Protein Name | Dna Repair Endonuclease XpfDna Excision Repair Protein Ercc-4Dna Repair Protein Complementing Xp-F CellsXeroderma Pigmentosum Group F-Complementing Protein |
| Database Links | Reactome: R-HSA-5685938Reactome: R-HSA-5696395Reactome: R-HSA-5696400Reactome: R-HSA-6782135Reactome: R-HSA-6783310 |
| Cellular Localisation | NucleusChromosomeLocalizes To Sites Of Dna Damage |
| Alternative Antibody Names | Anti-Dna Repair Endonuclease Xpf antibodyAnti-Dna Excision Repair Protein Ercc-4 antibodyAnti-Dna Repair Protein Complementing Xp-F Cells antibodyAnti-Xeroderma Pigmentosum Group F-Complementing Protein antibodyAnti-ERCC4 antibodyAnti-ERCC11 antibodyAnti-XPF antibody |
Information sourced from Uniprot.org
