| Short Description : | Rabbit polyclonal anti-ELKS/Rab6-interacting/CAST family member 1 for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ERC1 |
| Gene ID: | 23085 |
| Uniprot ID: | RB6I2_HUMAN |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Specificity: | RB6I2 Polyclonal Antibody detects endogenous levels of protein. |
| Function | Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. |
| Protein Name | Elks/Rab6-Interacting/Cast Family Member 1Erc-1Rab6-Interacting Protein 2 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeMembranePeripheral Membrane ProteinGolgi Apparatus MembranePresynaptic Cell MembraneCell ProjectionPodosomeRecruited On Golgi Membranes By Rab6a In A Gtp-Dependent MannerLocalized To The Cortex Of Myotube Podosomes |
| Alternative Antibody Names | Anti-Elks/Rab6-Interacting/Cast Family Member 1 antibodyAnti-Erc-1 antibodyAnti-Rab6-Interacting Protein 2 antibodyAnti-ERC1 antibodyAnti-ELKS antibodyAnti-KIAA1081 antibodyAnti-RAB6IP2 antibody |
Information sourced from Uniprot.org
