| Tissue Specificity | Widely expressed. Isoform 2 and isoform 4 are abundantly expressed in brain. Isoform 1 and isoform 3 are predominantly expressed in testis and thyroid, and isoform 1 predominates in other tissues tested. |
| Function | Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. |
| Protein Name | Elks/Rab6-Interacting/Cast Family Member 1Erc-1Rab6-Interacting Protein 2 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeMembranePeripheral Membrane ProteinGolgi Apparatus MembranePresynaptic Cell MembraneCell ProjectionPodosomeRecruited On Golgi Membranes By Rab6a In A Gtp-Dependent MannerLocalized To The Cortex Of Myotube Podosomes |
| Alternative Antibody Names | Anti-Elks/Rab6-Interacting/Cast Family Member 1 antibodyAnti-Erc-1 antibodyAnti-Rab6-Interacting Protein 2 antibodyAnti-ERC1 antibodyAnti-ELKS antibodyAnti-KIAA1081 antibodyAnti-RAB6IP2 antibody |
Information sourced from Uniprot.org
