Anti-EPSTI1 antibody (STJA0004669)

SKU:
STJA0004669
£140.50 - £415.50
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Host: Rabbit
Applications: IHC/ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Epithelial-Stromal Interaction Protein 1 is suitable for use in Immunohistochemistry and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Concentration: 0.66 mg/mL
Dilution Range: IHC 1:30-1:150
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: EPSTI1
Gene ID: 94240
Uniprot ID: ESIP1_HUMAN
Immunogen: Synthetic peptide of human EPSTI1
Tissue Specificity Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vitro. Expressed in blood mononuclear cells from patients with systemic lupus erythematosus (SLE).
Function Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation. Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages.
Protein Name Epithelial-Stromal Interaction Protein 1
Database Links Reactome: R-HSA-9696273
Alternative Antibody Names Anti-Epithelial-Stromal Interaction Protein 1 antibody
Anti-EPSTI1 antibody

Information sourced from Uniprot.org

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