Anti-Epoxide Hydrolase 1/EPHX1 antibody (21-455aa) [AT2E5] (STJA0041562)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenRecombinant human EPHX1 (21-455aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-Epoxide Hydrolase 1/EPHX1 (21-455aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT2E5 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-G affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EPHX1 |
| Gene ID | 2052 |
| Uniprot ID | HYEP_HUMAN |
| Accession Number | NP_000111 |
| Immunogen | Recombinant human EPHX1 (21-455aa) purified from E. coli |
| Immunogen Region | 21-455aa |
Additional Info
| Tissue Specificity | Found in liver. |
| Function | Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol. Binds 20(S)-hydroxycholesterol (20(S)-OHC). |
| Protein Name | Epoxide Hydrolase 1Epoxide HydrataseMicrosomal Epoxide HydrolaseMeh |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Microsome MembraneSingle-Pass Type Iii Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Epoxide Hydrolase 1 antibodyAnti-Epoxide Hydratase antibodyAnti-Microsomal Epoxide Hydrolase antibodyAnti-Meh antibodyAnti-EPHX1 antibodyAnti-EPHX antibodyAnti-EPOX antibody |
Information sourced from Uniprot.org