| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EPHX1 |
| Gene ID: | 2052 |
| Uniprot ID: | HYEP_HUMAN |
| Immunogen Region: | 20-320 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human EPHX1 (NP_000111.1). |
| Immunogen Sequence: | SRDKEETLPLEDGWWGPGTR SAAREDDSIRPFKVETSDEE IHDLHQRIDKFRFTPPLEDS CFHYGFNSNYLKKVISYWRN EFDWKKQVEILNRYPHFKTK IEGLDIHFIHVKPPQLPAGH TPKPLLMVHGWPGSFYEFYK IIPLLTDPKNHGLSDEHVFE VICPSIPGYGFSEASSKKGF NSVATARIFYKLMLRLGFQE FYIQGGDWGSLICTNMAQLV PSHVKGLHLNMALVLSNFS |
| Tissue Specificity | Found in liver. |
| Function | Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol. Binds 20(S)-hydroxycholesterol (20(S)-OHC). |
| Protein Name | Epoxide Hydrolase 1Epoxide HydrataseMicrosomal Epoxide HydrolaseMeh |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Microsome MembraneSingle-Pass Type Iii Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Epoxide Hydrolase 1 antibodyAnti-Epoxide Hydratase antibodyAnti-Microsomal Epoxide Hydrolase antibodyAnti-Meh antibodyAnti-EPHX1 antibodyAnti-EPHX antibodyAnti-EPOX antibody |
Information sourced from Uniprot.org