Anti-EPHA6 antibody (695-795 aa) [3D5B10] (STJ98028)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of EphA6 (aa695-795) expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-Ephrin type-A receptor 6 (695-795 aa) for use in WB and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 3D5B10 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EPHA6 |
| Gene ID | 285220 |
| Uniprot ID | EPHA6_HUMAN |
| Immunogen | Purified recombinant fragment of EphA6 (aa695-795) expressed in E. Coli. |
| Immunogen Region | 695-795 aa |
| Specificity | EphA6 Monoclonal Antibody detects endogenous levels of EphA6 protein. |
Additional Info
| Function | Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. |
| Protein Name | Ephrin Type-A Receptor 6Eph Homology Kinase 2Ehk-2Eph-Like Kinase 12Ek12 |
| Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928663Reactome: R-HSA-3928665 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Ephrin Type-A Receptor 6 antibodyAnti-Eph Homology Kinase 2 antibodyAnti-Ehk-2 antibodyAnti-Eph-Like Kinase 12 antibodyAnti-Ek12 antibodyAnti-EPHA6 antibodyAnti-EHK2 antibodyAnti-HEK12 antibody |
Information sourced from Uniprot.org