Anti-EpCAM antibody [PT0290R] (STJA0039633)

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STJA0039633
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Host: Rabbit
Applications: WB/IHC/IF/IP/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Epithelial Cell Adhesion Molecule is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation and ELISA research applications.
Clonality : Monoclonal
Clone ID : PT0290R
Conjugation: Unconjugated
Isotype: IgGk
Formulation: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification: Protein A
Dilution Range: IHC 1:200-1:1000
WB 1:1000-1:5000
IF 1:200-1:1000
ELISA 1:5000-1:20000
IP 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EPCAM
Gene ID: 4072
Uniprot ID: EPCAM_HUMAN
Specificity: Endogenous
Post Translational Modifications Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability.
Function May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Protein Name Epithelial Cell Adhesion Molecule
Ep-Cam
Adenocarcinoma-Associated Antigen
Cell Surface Glycoprotein Trop-1
Epithelial Cell Surface Antigen
Epithelial Glycoprotein
Egp
Epithelial Glycoprotein 314
Egp314
Hegp314
Ks 1/4 Antigen
Ksa
Major Gastrointestinal Tumor-Associated Protein Ga733-2
Tumor-Associated Calcium Signal Transducer 1
Cd Antigen Cd326
Database Links Reactome: R-HSA-202733
Cellular Localisation Lateral Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Tight Junction
Colocalizes With Cldn7 At The Lateral Cell Membrane And Tight Junction
Alternative Antibody Names Anti-Epithelial Cell Adhesion Molecule antibody
Anti-Ep-Cam antibody
Anti-Adenocarcinoma-Associated Antigen antibody
Anti-Cell Surface Glycoprotein Trop-1 antibody
Anti-Epithelial Cell Surface Antigen antibody
Anti-Epithelial Glycoprotein antibody
Anti-Egp antibody
Anti-Epithelial Glycoprotein 314 antibody
Anti-Egp314 antibody
Anti-Hegp314 antibody
Anti-Ks 1/4 Antigen antibody
Anti-Ksa antibody
Anti-Major Gastrointestinal Tumor-Associated Protein Ga733-2 antibody
Anti-Tumor-Associated Calcium Signal Transducer 1 antibody
Anti-Cd Antigen Cd326 antibody
Anti-EPCAM antibody
Anti-GA733-2 antibody
Anti-M1S2 antibody
Anti-M4S1 antibody
Anti-MIC18 antibody
Anti-TACSTD1 antibody
Anti-TROP1 antibody

Information sourced from Uniprot.org

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