Host: | Goat |
Applications: | Pep-ELISA/IF/IHC/FC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-EPB41L2/4.1G (593-604) is suitable for use in ELISA, Immunofluorescence, Immunohistochemistry and Flow Cytometry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary testing showed bands at approx 110+40kDa in Human Cerebellum lysatesafter 0.1µg/ml antibody staining (calculated MW of 113kDa according to NP_001422.1 These bands were succ |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | EPB41L2 |
Gene ID: | 2037 |
Uniprot ID: | E41L2_HUMAN |
Immunogen Region: | 593-604 |
Accession Number: | NP_001422.1; NP_001129026.1; NP_001186317.1; NP_001239589.1; NP_001337228.1; NP_001337230.1; NP_001337232.1; NP_001337233.1; NP_001337236.1; NP_001337243.1; NP_001337249.1 |
Specificity: | This antibody is reported to recognise all isoforms NP_001422.1 (iso a) , NP_001129026.1 (iso b) , NP_001186317.1 (iso c) , NP_001239589.1 (iso d) , NP_001337228.1 (iso e) , NP_001337230.1 (iso f) , NP_001337232.1 (iso g) , NP_001337233.1 (iso h) , N |
Immunogen Sequence: | RREVRSPTKAPH |
Function | Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase. |
Protein Name | Band 4.1-Like Protein 2Erythrocyte Membrane Protein Band 4.1-Like 2Generally Expressed Protein 4.14.1g |
Database Links | Reactome: R-HSA-6794361 |
Cellular Localisation | CytoplasmCytoskeletonCell CortexCell Membrane |
Alternative Antibody Names | Anti-Band 4.1-Like Protein 2 antibodyAnti-Erythrocyte Membrane Protein Band 4.1-Like 2 antibodyAnti-Generally Expressed Protein 4.1 antibodyAnti-4.1g antibodyAnti-EPB41L2 antibody |
Information sourced from Uniprot.org