| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-EP1 receptor/PTGER1 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.IHC: In paraffin embedded Human Kidney shows membranous staining in the epithelial cells of DCT. Recommended concentration: 1-2µg/ml. Paraffin embedded Human Spleen. Recommended concentra |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PTGER1 |
| Gene ID: | 5731 |
| Uniprot ID: | PE2R1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_000946.2 |
| Immunogen Sequence: | DSRRRWGAHGPRS |
| Post Translational Modifications | Phosphorylated. |
| Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. |
| Protein Name | Prostaglandin E2 Receptor Ep1 SubtypePge Receptor Ep1 SubtypePge2 Receptor Ep1 SubtypeProstanoid Ep1 Receptor |
| Database Links | Reactome: R-HSA-391908Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Prostaglandin E2 Receptor Ep1 Subtype antibodyAnti-Pge Receptor Ep1 Subtype antibodyAnti-Pge2 Receptor Ep1 Subtype antibodyAnti-Prostanoid Ep1 Receptor antibodyAnti-PTGER1 antibody |
Information sourced from Uniprot.org