| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Endosomal transmembrane epsin interactor 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ENTREP1 |
| Gene ID: |
9413 |
| Uniprot ID: |
EREP1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of C9orf61 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human C9orf61 |
| Post Translational Modifications | Monoubiquitinated at Lys-274, Lys-329 and Lys-365 by ITCH. |
| Function | Functions as an activator of the E3 ubiquitin protein ligase ITCH in the ubiquitination of the CXCL12-activated CXCR4 receptor. Thereby, triggers CXCR4 endocytosis and desensitization, negatively regulating the CXCL12/CXCR4 signaling pathway. |
| Protein Name | Endosomal Transmembrane Epsin Interactor 1Endosomal Transmembrane Binding With Epsin |
| Cellular Localisation | Early Endosome MembraneSingle-Pass Type I Membrane ProteinLate Endosome MembraneRecycling Endosome MembraneCell MembraneEnriched In Endosomes Compared To The Cell Membrane |
| Alternative Antibody Names | Anti-Endosomal Transmembrane Epsin Interactor 1 antibodyAnti-Endosomal Transmembrane Binding With Epsin antibodyAnti-ENTREP1 antibodyAnti-C9orf61 antibodyAnti-FAM189A2 antibodyAnti-X123 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
