| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Endosomal transmembrane epsin interactor 1 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ENTREP1 |
| Gene ID: | 9413 |
| Uniprot ID: | EREP1_HUMAN |
| Specificity: | This antibody detects endogenous levels of C9orf61 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human C9orf61 |
| Post Translational Modifications | Monoubiquitinated at Lys-274, Lys-329 and Lys-365 by ITCH. |
| Function | Functions as an activator of the E3 ubiquitin protein ligase ITCH in the ubiquitination of the CXCL12-activated CXCR4 receptor. Thereby, triggers CXCR4 endocytosis and desensitization, negatively regulating the CXCL12/CXCR4 signaling pathway. |
| Protein Name | Endosomal Transmembrane Epsin Interactor 1Endosomal Transmembrane Binding With Epsin |
| Cellular Localisation | Early Endosome MembraneSingle-Pass Type I Membrane ProteinLate Endosome MembraneRecycling Endosome MembraneCell MembraneEnriched In Endosomes Compared To The Cell Membrane |
| Alternative Antibody Names | Anti-Endosomal Transmembrane Epsin Interactor 1 antibodyAnti-Endosomal Transmembrane Binding With Epsin antibodyAnti-ENTREP1 antibodyAnti-C9orf61 antibodyAnti-FAM189A2 antibodyAnti-X123 antibody |
Information sourced from Uniprot.org