| Post Translational Modifications | The secreted form may be produced by intracellular processing. N-glycosylated. |
| Function | Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner. Has a strong preference for nucleoside diphosphates, preferentially hydrolyzes GDP, IDP, and UDP, with slower hydrolysis of CDP, ITP, GTP, CTP, ADP, and UTP and virtually no hydrolysis of ATP. The membrane bound form might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. |
| Protein Name | Ectonucleoside Triphosphate Diphosphohydrolase 6Ntpdase 6Cd39 Antigen-Like 2 |
| Database Links | Reactome: R-HSA-8850843 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinSecretedCell MembraneExists As A Secreted And Membrane-Bound Forms In The Medium Of Transfected CellsThe Secreted Form Is Predominant |
| Alternative Antibody Names | Anti-Ectonucleoside Triphosphate Diphosphohydrolase 6 antibodyAnti-Ntpdase 6 antibodyAnti-Cd39 Antigen-Like 2 antibodyAnti-ENTPD6 antibodyAnti-CD39L2 antibodyAnti-IL6ST2 antibody |
Information sourced from Uniprot.org
