| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Nucleoside diphosphate phosphatase ENTPD5 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ENTPD5 |
| Gene ID: |
957 |
| Uniprot ID: |
ENTP5_HUMAN |
| Specificity: |
This antibody detects endogenous levels of ENTPD5 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human ENTPD5 |
| Post Translational Modifications | N-glycosylated.high-mannose type. Glycosylation is not essential for enzymatic activity. |
| Function | Hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP. In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER. |
| Protein Name | Nucleoside Diphosphate Phosphatase Entpd5Cd39 Antigen-Like 4Er-UdpaseEctonucleoside Triphosphate Diphosphohydrolase 5Ntpdase 5Guanosine-Diphosphatase Entpd5Gdpase Entpd5Inosine Diphosphate Phosphatase Entpd5Nucleoside DiphosphataseUridine-Diphosphatase Entpd5Udpase Entpd5 |
| Database Links | Reactome: R-HSA-8850843Reactome: R-HSA-9660826 |
| Cellular Localisation | Endoplasmic ReticulumSecreted |
| Alternative Antibody Names | Anti-Nucleoside Diphosphate Phosphatase Entpd5 antibodyAnti-Cd39 Antigen-Like 4 antibodyAnti-Er-Udpase antibodyAnti-Ectonucleoside Triphosphate Diphosphohydrolase 5 antibodyAnti-Ntpdase 5 antibodyAnti-Guanosine-Diphosphatase Entpd5 antibodyAnti-Gdpase Entpd5 antibodyAnti-Inosine Diphosphate Phosphatase Entpd5 antibodyAnti-Nucleoside Diphosphatase antibodyAnti-Uridine-Diphosphatase Entpd5 antibodyAnti-Udpase Entpd5 antibodyAnti-ENTPD5 antibodyAnti-CD39L4 antibodyAnti-PCPH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
