| Host: | Mouse |
| Applications: | IHC/IF |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-eNOS is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Monoclonal |
| Clone ID : | SM4915 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol. |
| Purification: | Affinity purification |
| Dilution Range: | IHC/IF (H, R) 1:1000-1:2000/1:500-1:1000 |
| Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: | Nos3 |
| Gene ID: | 18127 |
| Uniprot ID: | NOS3_MOUSE |
| Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse eNOS |
| Function | Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. May play a significant role in normal and abnormal limb development. |
| Protein Name | Nitric Oxide Synthase 3Constitutive NosCnosEc-NosNos Type IiiNosiiiNitric Oxide Synthase - EndothelialEndothelial NosEnos |
| Database Links | Reactome: R-MMU-1222556Reactome: -MMU-1474151Reactome: -MMU-203615Reactome: -MMU-203641Reactome: -MMU-203754Reactome: -MMU-392154Reactome: -MMU-5218920Reactome: -MMU-9009391 |
| Cellular Localisation | MembraneCaveolaCytoplasmCytoskeletonGolgi ApparatusCell MembraneSpecifically Associates With Actin Cytoskeleton In The G2 Phase Of The Cell CycleWhich Is Favored By Interaction With Nosip And Results In A Reduced Enzymatic Activity |
| Alternative Antibody Names | Anti-Nitric Oxide Synthase 3 antibodyAnti-Constitutive Nos antibodyAnti-Cnos antibodyAnti-Ec-Nos antibodyAnti-Nos Type Iii antibodyAnti-Nosiii antibodyAnti-Nitric Oxide Synthase - Endothelial antibodyAnti-Endothelial Nos antibodyAnti-Enos antibodyAnti-Nos3 antibodyAnti-Ecnos antibody |
Information sourced from Uniprot.org

