Anti-Endophilin-A1/SH3GL2, Biotinylated antibody (Internal) {Biotin} (STJ73515)

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STJ73515-100
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Short Description :Goat polyclonal antibody anti-Endophilin-A1/SH3GL2, Biotinylated (Internal) is suitable for use in ELISA and Western Blot research applications.
Applications:Pep-ELISA/WB
Host:Goat
Reactivity:Human/Pig
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Biotin
Concentration:0.5 mg/mL
Purification:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution Range:Peptide ELISA: antibody detection limit dilution 1:64000.
WB: Approx 38kDa band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 40.0kDa according to NP_003017.1). Recommended concentration: 0.3-1µg/ml. See non-biotinylated pare
Formulation:0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage Instruction:Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol:SH3GL2
Gene ID:6456
Uniprot ID:SH3G2_HUMAN
Accession Number:NP_003017.1
Immunogen Region:Internal
Immunogen Sequence:CSLEFPTGDSTQPN.
Function Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.
Protein Name Endophilin-A1
Een-B1
Endophilin-1
Sh3 Domain Protein 2a
Sh3 Domain-Containing Grb2-Like Protein 2
Database Links Reactome: R-HSA-177504
Reactome: R-HSA-182971
Reactome: R-HSA-2132295
Reactome: R-HSA-432720
Reactome: R-HSA-432722
Reactome: R-HSA-437239
Reactome: R-HSA-6807004
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Reactome: R-HSA-8875360
Cellular Localisation Cytoplasm
Membrane
Peripheral Membrane Protein
Early Endosome
Presynapse
Alternative Antibody Names Anti-Endophilin-A1 antibody
Anti-Een-B1 antibody
Anti-Endophilin-1 antibody
Anti-Sh3 Domain Protein 2a antibody
Anti-Sh3 Domain-Containing Grb2-Like Protein 2 antibody
Anti-SH3GL2 antibody
Anti-CNSA2 antibody
Anti-SH3D2A antibody

Information sourced from Uniprot.org