Immunohistochemistry analysis of paraffin-embedded Mouse kidney tissue using Endomucin Rabbit mAb (STJ11107336) at a dilution of 1:300 (40x lens). High pressure antigen retrieval performed with 0. 01M Citrate Buffer (pH 6. 0) prior to immunohistochemistry staining.

Anti-Endomucin antibody (212-261 aa) [SRM] (STJ11107336)

SKU:
STJ11107336
£129.50 - £574.50
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Host: Rabbit
Applications: IHC-P/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: IHC-P:1:200-1:800
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: EMCN
Gene ID: 51705
Uniprot ID: MUCEN_HUMAN
Immunogen Region: 212-261 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 212-261 of human Endomucin (NP_057326.2).
Immunogen Sequence: LYRMCWKADPGTPENGNDQP QSDKESVKLLTVKTISHESG EHSAQGKTKN
Tissue Specificity Expressed in heart, kidney and lung.
Post Translational Modifications Highly O-glycosylated. Sialic acid-rich glycoprotein.
Function Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
Protein Name Endomucin
Endomucin-2
Gastric Cancer Antigen Ga34
Mucin-14
Muc-14
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Membrane
Consistently Localized To The Plasma Membrane And Less Abundantly To Golgi-Like Perinuclear Stacks
Isoform 2: Secreted
Alternative Antibody Names Anti-Endomucin antibody
Anti-Endomucin-2 antibody
Anti-Gastric Cancer Antigen Ga34 antibody
Anti-Mucin-14 antibody
Anti-Muc-14 antibody
Anti-EMCN antibody
Anti-EMCN2 antibody
Anti-MUC14 antibody

Information sourced from Uniprot.org

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