| Short Description : | Rabbit polyclonal anti-Ectoderm-neural cortex protein 1 (241-291 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ENC1 |
| Gene ID: | 8507 |
| Uniprot ID: | ENC1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human ENC1 at the amino acid range 241-291 |
| Immunogen Region: | 241-291 aa |
| Specificity: | This antibody detects endogenous levels of ENC1 at Human/Mouse |
| Post Translational Modifications | Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation. Quinone-induced oxidative stress increases its ubiquitination. |
| Function | Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin-mediated proteasomal degradation mechanism. |
| Protein Name | Ectoderm-Neural Cortex Protein 1Enc-1Kelch-Like Protein 37Nuclear Matrix Protein Nrp/BP53-Induced Gene 10 Protein |
| Database Links | |
| Cellular Localisation | Nucleus MatrixCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Ectoderm-Neural Cortex Protein 1 antibodyAnti-Enc-1 antibodyAnti-Kelch-Like Protein 37 antibodyAnti-Nuclear Matrix Protein Nrp/B antibodyAnti-P53-Induced Gene 10 Protein antibodyAnti-ENC1 antibodyAnti-KLHL37 antibodyAnti-NRPB antibodyAnti-PIG10 antibody |
Information sourced from Uniprot.org
