Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Ectoderm-neural cortex protein 1 (241-291 aa) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ENC1 |
Gene ID: |
8507 |
Uniprot ID: |
ENC1_HUMAN |
Immunogen Region: |
241-291 aa |
Specificity: |
This antibody detects endogenous levels of ENC1 at Human/Mouse |
Immunogen: |
Synthesized peptide derived from the human ENC1 at the amino acid range 241-291 |
Post Translational Modifications | Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation. Quinone-induced oxidative stress increases its ubiquitination. |
Function | Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin-mediated proteasomal degradation mechanism. |
Protein Name | Ectoderm-Neural Cortex Protein 1Enc-1Kelch-Like Protein 37Nuclear Matrix Protein Nrp/BP53-Induced Gene 10 Protein |
Cellular Localisation | Nucleus MatrixCytoplasmCytoskeleton |
Alternative Antibody Names | Anti-Ectoderm-Neural Cortex Protein 1 antibodyAnti-Enc-1 antibodyAnti-Kelch-Like Protein 37 antibodyAnti-Nuclear Matrix Protein Nrp/B antibodyAnti-P53-Induced Gene 10 Protein antibodyAnti-ENC1 antibodyAnti-KLHL37 antibodyAnti-NRPB antibodyAnti-PIG10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance