| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
EML1 |
| Gene ID: |
2009 |
| Uniprot ID: |
EMAL1_HUMAN |
| Immunogen Region: |
1-160 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human EML1 (NP_004425.2). |
| Immunogen Sequence: |
MEDGFSSYSSLYDTSSLLQF CNDDSASAASSMEVTDRIAS LEQRVQMQEDDIQLLKSALA DVVRRLNITEEQQAVLNRKG PTKARPLMQTLPLRTTVNNG TVLPKKPTGSLPSPSGVRKE TAVPATKSNIKRTSSSERVS PGGRRESNGDSRGNRNRTGS |
| Tissue Specificity | Ubiquitous.expressed in most tissues with the exception of thymus and peripheral blood lymphocytes. |
| Function | Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se. |
| Protein Name | Echinoderm Microtubule-Associated Protein-Like 1Emap-1Huemap-1 |
| Cellular Localisation | CytoplasmPerinuclear RegionCytoskeletonDetected In Cytoplasmic PunctaeCo-Localizes With MicrotubulesEnriched In Perinuclear Regions During Interphase And In The Region Of Spindle Microtubules During MetaphaseEnriched At The Midzone During Telophase And CytokinesisDetected At Growth Cones In Neurons |
| Alternative Antibody Names | Anti-Echinoderm Microtubule-Associated Protein-Like 1 antibodyAnti-Emap-1 antibodyAnti-Huemap-1 antibodyAnti-EML1 antibodyAnti-EMAP1 antibodyAnti-EMAPL antibodyAnti-EMAPL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
