| Host: | Rabbit |
| Applications: | IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Endomucin (201-250 aa) is suitable for use in Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IF 1:200-1:1000ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EMCN |
| Gene ID: | 51705 |
| Uniprot ID: | MUCEN_HUMAN |
| Immunogen Region: | 201-250 aa |
| Specificity: | Endomucin Polyclonal Antibody detects endogenous levels of Endomucin protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human Mucin-14 at the amino acid range 201-250 |
| Post Translational Modifications | Highly O-glycosylated. Sialic acid-rich glycoprotein. |
| Function | Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. |
| Protein Name | EndomucinEndomucin-2Gastric Cancer Antigen Ga34Mucin-14Muc-14 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinMembraneConsistently Localized To The Plasma Membrane And Less Abundantly To Golgi-Like Perinuclear StacksIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Endomucin antibodyAnti-Endomucin-2 antibodyAnti-Gastric Cancer Antigen Ga34 antibodyAnti-Mucin-14 antibodyAnti-Muc-14 antibodyAnti-EMCN antibodyAnti-EMCN2 antibodyAnti-MUC14 antibody |
Information sourced from Uniprot.org