| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-EMB (33-260) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EMB |
| Gene ID: |
133418 |
| Uniprot ID: |
EMB_HUMAN |
| Immunogen Region: |
33-260 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 33-260 of human EMB (NP_940851.1). |
| Immunogen Sequence: |
DGSAPDSPFTSPPLREEIMA NNFSLESHNISLTEHSSMPV EKNITLERPSNVNLTCQFTT SGDLNAVNVTWKKDGEQLEN NYLVSATGSTLYTQYRFTII NSKQMGSYSCFFREEKEQRG TFNFKVPELHGKNKPLISYV GDSTVLTCKCQNCFPLNWTW YSSNGSVKVPVGVQMNKYVI NGTYANETKLKITQLLEEDG ESYWCRALFQLGESEEHIEL VVLSYLVP |
| Function | Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1, SLC16A6 and SLC16A7 to the cell membrane. |
| Protein Name | Embigin |
| Database Links | Reactome: R-HSA-433692 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSynapseLocalizes To The Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Embigin antibodyAnti-EMB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
