Anti-ELP5 antibody (17-316) (STJ117062)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ELP5 (17-316) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ELP5 |
| Gene ID | 23587 |
| Uniprot ID | ELP5_HUMAN |
| Immunogen Region | 17-316 |
| Immunogen Sequence | MLDSLLALGGLVLLRDSVEW EGRSLLKALVKKSALCGEQV HILGCEVSEEEFREGFDSDI NNRLVYHDFFRDPLNWSKTE EAFPGGPLGALRAMCKRTDP VPVTIALDSLSWLLLRLPCT TLCQVLHAVSHQDSCPGDSS SVGKVSVLGLLHEELHGPGP VGALSSLAQTEVTLGGTMGQ ASAHILCRRPRQRPTDQTQW FSILPDFSLDLQEGPSVESQ PYSDPHIPPVDPTTHLTFN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 17-316 of human ELP5 (NP_056177.3). |
Additional Info
| Tissue Specificity | Ubiquitously expressed with high levels in heart, brain, liver, skeletal muscle and testis. |
| Post Translational Modifications | Tyrosine-phosphorylated. |
| Function | Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. Involved in cell migration. |
| Protein Name | Elongator Complex Protein 5Dermal Papilla-Derived Protein 6S-Phase 2 Protein |
| Database Links | Reactome: R-HSA-3214847 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Elongator Complex Protein 5 antibodyAnti-Dermal Papilla-Derived Protein 6 antibodyAnti-S-Phase 2 Protein antibodyAnti-ELP5 antibodyAnti-C17orf81 antibodyAnti-DERP6 antibodyAnti-HSPC002 antibodyAnti-MSTP071 antibody |
Information sourced from Uniprot.org