| Post Translational Modifications | N-Glycosylated. |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and unsaturated acyl-CoA substrates with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
| Protein Name | Very Long Chain Fatty Acid Elongase 33-Keto Acyl-Coa Synthase Elovl3Cold-Inducible Glycoprotein Of 30 KdaElovl Fatty Acid Elongase 3Elovl Fa Elongase 3Elongation Of Very Long Chain Fatty Acids Protein 3Very Long Chain 3-Ketoacyl-Coa Synthase 3Very Long Chain 3-Oxoacyl-Coa Synthase 3 |
| Database Links | Reactome: R-HSA-2046105Reactome: R-HSA-2046106Reactome: R-HSA-75876Reactome: R-HSA-9844594 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Very Long Chain Fatty Acid Elongase 3 antibodyAnti-3-Keto Acyl-Coa Synthase Elovl3 antibodyAnti-Cold-Inducible Glycoprotein Of 30 Kda antibodyAnti-Elovl Fatty Acid Elongase 3 antibodyAnti-Elovl Fa Elongase 3 antibodyAnti-Elongation Of Very Long Chain Fatty Acids Protein 3 antibodyAnti-Very Long Chain 3-Ketoacyl-Coa Synthase 3 antibodyAnti-Very Long Chain 3-Oxoacyl-Coa Synthase 3 antibodyAnti-ELOVL3 antibodyAnti-CIG30 antibody |
Information sourced from Uniprot.org
