Anti-ELOVL2 antibody (247-296) (STJ119753)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ELOVL2 (247-296) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ELOVL2 |
| Gene ID | 54898 |
| Uniprot ID | ELOV2_HUMAN |
| Immunogen Region | 247-296 |
| Immunogen Sequence | ILFLNFYVQTYRKKPMKKDM QEPPAGKEVKNGFSKAYFTA ANGVMNKKAQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 247-296 of human ELOVL2 (NP_060240.3). |
Additional Info
| Tissue Specificity | Liver and testis. |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
| Protein Name | Very Long Chain Fatty Acid Elongase 23-Keto Acyl-Coa Synthase Elovl2Elovl Fatty Acid Elongase 2Elovl Fa Elongase 2Elongation Of Very Long Chain Fatty Acids Protein 2Very Long Chain 3-Ketoacyl-Coa Synthase 2Very Long Chain 3-Oxoacyl-Coa Synthase 2 |
| Database Links | Reactome: R-HSA-2046105Reactome: R-HSA-2046106Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Very Long Chain Fatty Acid Elongase 2 antibodyAnti-3-Keto Acyl-Coa Synthase Elovl2 antibodyAnti-Elovl Fatty Acid Elongase 2 antibodyAnti-Elovl Fa Elongase 2 antibodyAnti-Elongation Of Very Long Chain Fatty Acids Protein 2 antibodyAnti-Very Long Chain 3-Ketoacyl-Coa Synthase 2 antibodyAnti-Very Long Chain 3-Oxoacyl-Coa Synthase 2 antibodyAnti-ELOVL2 antibodyAnti-ELG3 antibodyAnti-SSC2 antibody |
Information sourced from Uniprot.org