| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ELMOD2 |
| Gene ID: | 255520 |
| Uniprot ID: | ELMD2_HUMAN |
| Immunogen Region: | 1-130 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of mouse ELMOD2 (Q8BGF6). |
| Immunogen Sequence: | MFVSLWEFFYGHFFRFWMKW LLRQMTGKCELQRIFDTYGG AQRTYRIENSLTYSKNKVLQ NATRVAQSELDRCIANIMKE KNICSEKDTSFQICMRTCLL QITGYKQLYHDVENVRKKPY DSANAQHEKM |
| Tissue Specificity | Alveolar cells (morphologically type II cells) and alveolar macrophages (at protein level). Expressed in brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach and testis. In lung it is expressed in alveolar macrophages and alveolar walls. |
| Function | Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses. |
| Protein Name | Elmo Domain-Containing Protein 2 |
| Alternative Antibody Names | Anti-Elmo Domain-Containing Protein 2 antibodyAnti-ELMOD2 antibody |
Information sourced from Uniprot.org