• STJ70113 (0. 3µg/ml) staining of Human Frontal Cortex (A) , Mouse (B) and Rat (C) Brain lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.
  • STJ70113 (0. 3µg/ml) staining of Jurkat cell lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.

Anti-ELMO1 antibody (C-Term) (STJ70113)

SKU:
STJ70113-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog/Cow/Zebrafish
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-ELMO1 (C-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.1-0.3µg/ml
ELISA-antibody detection limit dilution 1:128000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ELMO1
Gene ID: 9844
Uniprot ID: ELMO1_HUMAN
Immunogen Region: C-Term
Accession Number: NP_055615.8; NP_569709.1; NP_001034548.1
Specificity: This antibody is expected to recognise both human isoforms of this protein. NP_569709.1 and NP_001034548.1 represent the same isoform.
Immunogen Sequence: PKEPSNYDFVYDCN
Post Translational Modifications Phosphorylated by HCK.
Function Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Protein Name Engulfment And Cell Motility Protein 1
Protein Ced-12 Homolog
Database Links Reactome: R-HSA-164944
Reactome: R-HSA-2029482
Reactome: R-HSA-4420097
Reactome: R-HSA-8849471
Reactome: R-HSA-9664422
Cellular Localisation Cytoplasm
Cell Membrane
Translocation To Plasma Membrane Seems To Be Mediated By Dock1 And Crk
Alternative Antibody Names Anti-Engulfment And Cell Motility Protein 1 antibody
Anti-Protein Ced-12 Homolog antibody
Anti-ELMO1 antibody
Anti-KIAA0281 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance