| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ELF1 (1-210) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ELF1 |
| Gene ID: |
1997 |
| Uniprot ID: |
ELF1_HUMAN |
| Immunogen Region: |
1-210 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human ELF1 (NP_758961.1). |
| Immunogen Sequence: |
MAAVVQQNDLVFEFASNVME DERQLGDPAIFPAVIVEHVP GADILNSYAGLACVEEPNDM ITESSLDVAEEEIIDDDDDD ITLTVEASCHDGDETIETIE AAEALLNMDSPGPMLDEKRI NNNIFSSPEDDMVVAPVTHV SVTLDGIPEVMETQQVQEKY ADSPGASSPEQPKRKKGRKT KPPRPDSPATTPNISVKKKN KDGKGNTIYL |
| Tissue Specificity | In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis. |
| Function | Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. |
| Protein Name | Ets-Related Transcription Factor Elf-1E74-Like Factor 1 |
| Database Links | Reactome: R-HSA-8939245Reactome: R-HSA-8939247 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ets-Related Transcription Factor Elf-1 antibodyAnti-E74-Like Factor 1 antibodyAnti-ELF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
