Anti-ELF1 antibody (1-210) (STJ28984)

SKU:
STJ28984

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Host: Rabbit
Applications: IF/ICC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: IF/ICC:1:50-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ELF1
Gene ID: 1997
Uniprot ID: ELF1_HUMAN
Immunogen Region: 1-210
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human ELF1 (NP_758961.1).
Immunogen Sequence: MAAVVQQNDLVFEFASNVME DERQLGDPAIFPAVIVEHVP GADILNSYAGLACVEEPNDM ITESSLDVAEEEIIDDDDDD ITLTVEASCHDGDETIETIE AAEALLNMDSPGPMLDEKRI NNNIFSSPEDDMVVAPVTHV SVTLDGIPEVMETQQVQEKY ADSPGASSPEQPKRKKGRKT KPPRPDSPATTPNISVKKKN KDGKGNTIYL
Tissue Specificity In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
Function Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.
Protein Name Ets-Related Transcription Factor Elf-1
E74-Like Factor 1
Database Links Reactome: R-HSA-8939245
Reactome: R-HSA-8939247
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Ets-Related Transcription Factor Elf-1 antibody
Anti-E74-Like Factor 1 antibody
Anti-ELF1 antibody

Information sourced from Uniprot.org

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