| Short Description : | Rabbit polyclonal Endosome/Lysosome-Associated Apoptosis And Autophagy Regulator 1 (30-130 aa) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ELAPOR1 |
| Gene ID: | 57535 |
| Uniprot ID: | ELAP1_HUMAN |
| Immunogen Region: | 30-130 aa |
| Immunogen Sequence: | LWAGTAFQVTQGTGPELHAC KESEYHYEYTACDSTGSRWR VAVPHTPGLCTSLPDPVKGT ECSFSCNAGEFLDMKDQSCK PCAEGRYSLGTGIRFDEWDE L |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-130 of human ELAPOR1. (NP_065826.2). |
| Tissue Specificity | Expressed in normal endometrium but overexpressed in endometroid tumors. |
| Function | May protect cells from cell death by inducing cytosolic vacuolization and up-regulating the autophagy pathway. May play a role in apoptosis and cell proliferation through its interaction with HSPA5. |
| Protein Name | Endosome/Lysosome-Associated Apoptosis And Autophagy Regulator 1Estrogen-Induced Gene 121 Protein |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinLate Endosome MembraneGolgi ApparatusTrans-Golgi Network MembraneLysosome MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Endosome/Lysosome-Associated Apoptosis And Autophagy Regulator 1 antibodyAnti-Estrogen-Induced Gene 121 Protein antibodyAnti-ELAPOR1 antibodyAnti-EIG121 antibodyAnti-KIAA1324 antibodyAnti-UNQ2426 antibodyAnti-PRO4985 antibody |
Information sourced from Uniprot.org
