Tissue Specificity | Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
Function | Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1. tRNAs are then processed by TRNT1. |
Protein Name | Zinc Phosphodiesterase Elac Protein 1Deleted In Ma29Elac Homolog Protein 1Ribonuclease Z 1Rnase Z 1Trna 3 Endonuclease 1Trnase Z 1 |
Cellular Localisation | CytoplasmCytosolNucleusMainly Cytosolic |
Alternative Antibody Names | Anti-Zinc Phosphodiesterase Elac Protein 1 antibodyAnti-Deleted In Ma29 antibodyAnti-Elac Homolog Protein 1 antibodyAnti-Ribonuclease Z 1 antibodyAnti-Rnase Z 1 antibodyAnti-Trna 3 Endonuclease 1 antibodyAnti-Trnase Z 1 antibodyAnti-ELAC1 antibodyAnti-D29 antibody |
Information sourced from Uniprot.org