| Post Translational Modifications | Ubiquitinated in U2OS osteosarcoma cells and is rapidly degraded by proteasome as cells exit the cell cycle exit. |
| Function | Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms. |
| Protein Name | Ep300-Interacting Inhibitor Of Differentiation 121 Kda Prb-Associated ProteinCrebbp/Ep300 Inhibitory Protein 1E1a-Like Inhibitor Of Differentiation 1Eid-1 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmMay Shuttle Between Nucleus And Cytoplasm |
| Alternative Antibody Names | Anti-Ep300-Interacting Inhibitor Of Differentiation 1 antibodyAnti-21 Kda Prb-Associated Protein antibodyAnti-Crebbp/Ep300 Inhibitory Protein 1 antibodyAnti-E1a-Like Inhibitor Of Differentiation 1 antibodyAnti-Eid-1 antibodyAnti-EID1 antibodyAnti-C15orf3 antibodyAnti-CRI1 antibodyAnti-RBP21 antibodyAnti-PNAS-22 antibodyAnti-PTD014 antibody |
Information sourced from Uniprot.org
