Anti-EHD2 antibody (420-450) (STJ500852)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid 420-450 on human EH-Domain Containing Protein 2.
General Information
| Short Description | Rabbit polyclonal antibody anti-EHD2 (420-450) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.55 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:100 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | EHD2 |
| Gene ID | 30846 |
| Uniprot ID | EHD2_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid 420-450 on human EH-Domain Containing Protein 2. |
| Immunogen Region | 420-450 |
Additional Info
| Tissue Specificity | Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle. |
| Function | ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane. |
| Protein Name | Eh Domain-Containing Protein 2Past Homolog 2 |
| Database Links | Reactome: R-HSA-983231 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideMembraneCaveolaEndosome MembraneCytoplasmCytosolColocalizes With Glut4 In Intracellular Tubulovesicular Structures That Are Associated With Cortical F-ActinColocalizes With Fer1l5 At Plasma Membrane In Myoblasts And Myotubes |
| Alternative Antibody Names | Anti-Eh Domain-Containing Protein 2 antibodyAnti-Past Homolog 2 antibodyAnti-EHD2 antibodyAnti-PAST2 antibody |
Information sourced from Uniprot.org