• Immunohistochemistry of mouse lung with Anti-EHD2 primary antibody (STJ500852) at 1:50 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-EHD2 antibody (420-450) (STJ500852)

SKU:
STJ500852-100

£441.50
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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EHD2 (420-450) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.55 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:50-1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: EHD2
Gene ID: 30846
Uniprot ID: EHD2_HUMAN
Immunogen Region: 420-450
Immunogen: Synthetic peptide taken within amino acid 420-450 on human EH-Domain Containing Protein 2.
Tissue Specificity Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.
Function ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane.
Protein Name Eh Domain-Containing Protein 2
Past Homolog 2
Database Links Reactome: R-HSA-983231
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Membrane
Caveola
Endosome Membrane
Cytoplasm
Cytosol
Colocalizes With Glut4 In Intracellular Tubulovesicular Structures That Are Associated With Cortical F-Actin
Colocalizes With Fer1l5 At Plasma Membrane In Myoblasts And Myotubes
Alternative Antibody Names Anti-Eh Domain-Containing Protein 2 antibody
Anti-Past Homolog 2 antibody
Anti-EHD2 antibody
Anti-PAST2 antibody

Information sourced from Uniprot.org

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