| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Embryonal Fyn-associated substrate (108-158 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EFS |
| Gene ID: | 10278 |
| Uniprot ID: | EFS_HUMAN |
| Immunogen Region: | 108-158 aa |
| Specificity: | This antibody detects endogenous levels of EFS at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human EFS at the amino acid range 108-158 |
| Post Translational Modifications | Phosphorylated on multiple tyrosine residues. Phosphorylated on tyrosines by FYN and SRC. |
| Function | Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES. |
| Protein Name | Embryonal Fyn-Associated SubstrateHefsCas Scaffolding Protein Family Member 3 |
| Alternative Antibody Names | Anti-Embryonal Fyn-Associated Substrate antibodyAnti-Hefs antibodyAnti-Cas Scaffolding Protein Family Member 3 antibodyAnti-EFS antibodyAnti-CASS3 antibody |
Information sourced from Uniprot.org
