| Short Description : | Rabbit polyclonal anti-EF-hand domain-containing protein D2 (13-63 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EFHD2 |
| Gene ID: | 79180 |
| Uniprot ID: | EFHD2_HUMAN |
| Immunogen: | Synthesized peptide derived from the human EFHD2 at the amino acid range 13-63 |
| Immunogen Region: | 13-63 aa |
| Specificity: | This antibody detects endogenous levels of EFHD2 at Human/Mouse/Rat |
| Function | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
| Protein Name | Ef-Hand Domain-Containing Protein D2Swiprosin-1 |
| Database Links | Reactome: R-HSA-9013405 |
| Cellular Localisation | Membrane RaftIn A Mouse Immature B-Cell Line Wehi-231 |
| Alternative Antibody Names | Anti-Ef-Hand Domain-Containing Protein D2 antibodyAnti-Swiprosin-1 antibodyAnti-EFHD2 antibodyAnti-SWS1 antibody |
Information sourced from Uniprot.org
